Speaker Details

Speaker

JENS C. BRUNING

Max Planck Institute

Dr. Jens Brüning is Director of the Max Planck Institute for Metabolism Research in Cologne and Director at the Policlinic for Endocrinology, Diabetes and Preventive Medicine at the University Hospital in Cologne.

His research focusses on elucidating the CNS-dependent regulation of energy and glucose metabolism. These studies revealed a previously unappreciated role for insulin action in the central nervous system (CNS) to control organismal glucose homeostasis and insulin sensitivty. His group has defined distinct Agouti-related peptide (AgRP)-expressing neurons in the hypothalamus as critical mediators of insulin's metabolic actions, revealed the molecular mechanisms of insulin action in these neurons as well as their alterations in obesity. More recently, through the use of neurocircuitry mapping techniques his group defined the projections of these AgRP-neurons within the CNS, which govern insulin-dependent control of systemic insulin sensitivty via the regulation of autonomic innervation.

Symposium Faculty

Elçin Ünal

University of California, Berkeley

Ali Deniz Güler

University of Virginia

Yasemin Sancak

Harvard Medical School

Ömer Yılmaz

Massachusetts Institute of Technology

Joseph L. Goldstein

University of Texas Southwestern Medical Center at Dallas

Michael S. Brown

University of Texas, Southwestern Medical Center

Linda Partridge

University College London

Bruce Spiegelman

Harvard Medical School

Leslie Vosshall

The Rockefeller University

Jens C. Brüning

Max Planck Institute

Ronald M. Evans

Salk Institute

Michael Czech

University of Massachusetts Medical School

Jean Schaffer

Washington University

Gerald Shulman

Yale University

Brenda Schulman

St. Jude Children's Research Hospital

Vamsi Mootha

Massachusetts General Hosptial
Columbia University

Peter Walter

University of California, San Francisco