Speaker

DENİZ ATASOY

Assistant Professor, Physiology, School of Medicine
İstanbul Medipol University

Deniz Atasoy has received his B.S degree at Bilkent University, Department of Molecular Biology and Genetics. In 2001-2007 he received his PhD at University of Texas Southwestern Medical Center, Dallas, Texas, USA, Center for Basic Neuroscience Research. He received Outstanding Young Scientist Awards from the Turkish Academy of Sciences (TÜBA) in 2014. He also received Eczacibasi Foundation Medical Award, Marie S. Curie, (IF) fellowship and The Scientific and Technological Research Council of Turkey (TUBITAK) fellowship in 2015. He has authored over 20 publications in journals including Nature, Cell, Science and Nature Neuroscience. He is Assistant Professor in Istanbul Medipol University, School of Medicine, Department of Physiology.

Abstract


Optogenetic Dissection of Neuronal Circuits Regulating Feeding Behavior
Dr. Deniz Atasoy
İstanbul Medipol University, Medical School, Department of Physiology, İstanbul

New tools for mapping and manipulating molecularly defined neural circuits have improved the understanding of how the central nervous system regulates appetite. Activation of starvation-sensitive AGRP neurons can rapidly elicit behavioral state similar to food deprivation, which present an entry point for reverse-engineering neural circuits for hunger. We mapped functional synaptic interactions of AGRP neurons with multiple cell populations in mice and probed the contribution of these distinct circuits to feeding behaviour using optogenetic and pharmacogenetic techniques. We have also developed tools for detailed structural analysis of AGRP neuronal connections using serial-section electron microscopy. Our results characterized some basic features of functional and anatomical circuit organization for AGRP axon projections.

Symposium Faculty

ALAN D. ATTIE

Professor, Biochemistry
University of Wisconsin

LAURIE H. GLIMCHER

Professor, Dean of Cornell Medical School

ROBERT FARESE

Professor, Genetics and Complex Diseases
Harvard T.H. Chan School of Public Health

GÖKHAN HOTAMIŞLIGİL

Professor, Genetics and Metabolism and Nutrition
Harvard University

BRIAN KOBILKA

Professor, Department of Molecular and Cellular Physiology
Stanford University

SUSANNE MANDRUP

Professor, Biochemistry and Molecular Biology
University of Southern Denmark

EMILIE MARCUS

CEO of Cell Press and Editor of Cell

RUSLAN MEDZHITOV

David W. Wallace Professor of Immunobiology; Investigator, Howard Hughes Medical Institute, Yale University, HHMI

IRA TABAS

Professor, Anatomy Cell Biology
Columbia University

PETER TONTONOZ

Professor, Pathology and Laboratory Medicine
University of California Los Angeles

DENİZ ATASOY

Assistant Professor, Physiology, School of Medicine
İstanbul Medipol University

EBRU ERBAY

Assistant Professor, Molecular Biology and Genetics
Bilkent University

KIVANÇ BİRSOY

Assistant Professor, Molecular Biology and Genetics
Rockefeller University

LALE OZCAN

Assistant Professor, Department of Medicine
Columbia University Medical Center